Effect of trapidil on the sciatic nerve with crush injury: a light microscopic study

نویسندگان

  • Zeliha Kurtoglu
  • Ahmet Hakan Ozturk
  • Celal Bagdatoglu
  • Aysegul Turac
  • Handan Camdeviren
  • Deniz Uzmansel
  • Mustafa Aktekin
چکیده

In this study, 40 female albino wistar rats were used. The sciatic nerves were crushed for 20 seconds by a jeweler’s forceps. A single dose of 8 mg/kg of trapidil was administered to the treatment group intraperitoneally. After the crush injury, the crush site was excised on 2nd, 7th, 15th, 30th, and 45th days, fixed in formalin and then prepared for routine histological evaluation. Each section was stained with toluidin blue. Myelin thicknesses were measured by an ocular micrometer.

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تاریخ انتشار 2004